Wednesday, 17 December 2014   
IMI launches €115 million Calls for proposals to develop vaccines & medicines of the future
The Innovative Medicines Initiative (IMI) and the Bill and Melinda Gates Foundation are to collaborate on a project to improve vaccines against whooping cough. Whooping cough, also known as pertussis, is an infectious disease caused by the Bordetella pertussis bacterium and characterised by severe coughing fits. Worldwide, there are around 16 million cases and 195 000 deaths from pertussis in children every year. Vaccines against pertussis do exist, but a resurgence in the number of cases in certain countries is cause for concern. This new project will make it possible to refine current vaccination schedules to make them more effective, and facilitate the development of new and improved vaccine formulations.
 
Thursday, 11 December 2014   
'Trojan horse' proteins used to target hard-to-reach cancers
Scientists at Brunel University London have found a way of targeting hard-to-reach cancers and degenerative diseases using nanoparticles, but without causing the damaging side effects the treatment normally brings. In a huge step forward in the use of nanomedicine, the research helped discover proteins in the blood that disguise nanoparticles so they are absorbed into cells without causing inflammation and destroying healthy cells. Two studies, Complement activation by carbon nanotubes and its influence on the phagocytosis and cytokine response by macrophages and Complement deposition on nanoparticles can modulate immune responses by macrophage, B and T cells, found that carbon nanotubes (CNTs) triggered a chain reaction in the complement system, which is part of the innate immune system and is responsible for clearing pathogens and toxins.
 
Monday, 08 December 2014   
Rule of 3: Hormone triplet offers hope for obesity and diabetes
Recently, the researchers had constructed several single molecules with dual hormone action. Now, for the first time, the researchers succeeded in designing a substance that combines three metabolically active hormone components (GLP-1, GIP and glucagon) and offers unmatched potency to fight metabolic diseases in pre-clinical trials. The team headed by physician scientist Matthias Tschöp (Helmholtz Diabetes Center at HMGU and Metabolic Diseases Chair at TUM) and peptide chemist Richard DiMarchi (Indiana University) has been cooperating for almost a decade to invent improved therapeutics for type 2 diabetes and obesity. One of their novel approaches is to design molecules that combine the effects of specific metabolic hormones.
 

Research & Development

IMI launches €115 million Calls for proposals to develop vaccines & medicines of the future

The Innovative Medicines Initiative (IMI) and the Bill and Melinda Gates Foundation are to collaborate on a project to improve...

'Trojan horse' proteins used to target hard-to-reach cancers

Scientists at Brunel University London have found a way of targeting hard-to-reach cancers and degenerative diseases using nanoparticles, but without...

Rule of 3: Hormone triplet offers hope for obesity and diabetes

Recently, the researchers had constructed several single molecules with dual hormone action. Now, for the first time, the researchers succeeded...

The intestinal immune system controls the body weight

A group of UCL researchers (Louvain Drug Research Institute) identified an unsuspected mechanism impacting the development of obesity and diabetes...

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Conferences & Events

mHealth Summit Europe 2015 and eHealth Week join forces

11 - 12 May 2015, Riga, Latvia. The mHealth Summit Europe will be back in 2015 as a part of eHealth Week in Riga, Latvia. The Summit will be opening...

European Telemedicine Conference 2014

7 - 8 October 2014, Rome, Italy. The European Telemedicine Conference (ETC) 2014 will combine the efforts of several leading European Healthcare Organisations into one powerful event. The conference will...

Medical Entrepreneur Start-up Hospital - M.E.S.H Camp 2014

17 - 18 September 2014, Berlin, Germany. Anyone who's ever tried to launch a start-up knows how hard it is. It takes all you've got to succeed. DocCheck Guano organises...

Biovision presents its selection of 44 promising life sciences businesses and projects

5 - 6 June 2014, Lyon, France. Biovision, the annual forum on future-oriented research in life sciences, today announces the list of biotech and medtech companies and projects selected for...

Delegates from more than 30 countries to share the benefits of eHealth at WoHIT 2014

2 - 4 April 2014, Nice, France. The World of Health IT Conference and Exhibition 2014 (WoHIT 2014), taking place in Nice, France, presents a comprehensive international programme with 18...

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EC Pharmaceuticals

Medicines for children: more research, more availability and more information compared with 5 years ago

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Recently, the Commission has publisheed a progress report on medicines for children covering the five years since the Paediatric Regulation came into force. This preliminary snapshot points to improvements in...

New symbol to identify medicines undergoing additional monitoring

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An inverted triangle will shortly appear on the inside leaflet of certain medicinal products on the EU market, following a legal act adopted by the European Commission today. The symbol...

Launch of EU Rapid Alert platform for human Tissues and Cells

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A secure alert platform launched by the European Commission will improve the safety of patients undergoing transplantation and medical procedures involving human tissues and cells, e.g. bone marrow, cornea, skin,...

Commission proposes faster access to medicines for patients

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Medicines should enter the market faster. With this intention the European Commission has proposed today to streamline and reduce the duration of national decisions on pricing and reimbursement of medicines....

Pricing and reimbursement of medicines: Commission consults on EU transparency rules

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The European Commission has launched a public consultation in view of modernising rules on the transparency of Member States’ decisions regarding the pricing and reimbursement of medicines. The consultation invites...

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EMA News

Europe to boost cooperation with international partners on generics

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The European Union's decentralised procedure is being used as a model to accelerate the assessment of applications for generic medicines as part of the International Generic Drug Regulators Pilot(IGDRP). The...

European Medicines Agency recommends 39 medicines for human use for marketing authorisation in first half of 2014

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Thirty-nine medicines for human use were recommended for marketing authorisation by the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) in the first half of 2014, compared...

EMA publishes 2013 annual report

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The European Medicines Agency (EMA) has published today its 2013 annual report. In 2013, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended 81 medicines for human use...

Committee for orphan medicines - overview of 2013 and looking ahead

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A total of 11 out of 81 medicines recommended for marketing authorisation by the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) in 2013 were intended...

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