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Roche
RocheHeadquartered in Basel, Switzerland, Roche is one of the world's leading research-focused healthcare groups in the fields of pharmaceuticals and diagnostics. As the world's biggest biotech company and an innovator of products and services for the early detection, prevention, diagnosis and treatment of diseases, the Group contributes on a broad range of fronts to improving people's health and quality of life. Roche is the world leader in in-vitro diagnostics and drugs for cancer and transplantation, and is a market leader in virology. It is also active in other major therapeutic areas such as autoimmune diseases, inflammatory and metabolic disorders and diseases of the central nervous system. In 2007 sales by the Pharmaceuticals Division totalled 36.8 billion Swiss francs, and the Diagnostics Division posted sales of 9.3 billion francs. Roche has R&D agreements and strategic alliances with numerous partners, including majority ownership interests in Genentech and Chugai, and invested over 8 billion Swiss francs in R&D in 2007. Worldwide, the Group employs about 80,000 people. Additional information is available on the Internet at www.roche.com.

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1 Phase III study of Avastin in advanced stomach cancer did not meet primary endpoint 243
2 Herceptin now approved in the EU for patients with HER2-positive advanced stomach cancer 408
3 Roche invests about 190 Mio Swiss Francs in infusion-free administration device 445
4 Greater chances of cure for patients with HER2-positive early breast cancer when treated with one year of Herceptin 676
5 European medical advisory committee does not recommend approval of Avastin for deadly form of brain cancer 559
6 Roche reports further accelerated sales growth in third quarter 906
7 Herceptin provides impressive survival benefit for patients with high levels of HER2 in their stomach cancer 739
8 MabThera approved in Europe for use in patients with previously-treated chronic lymphocytic leukaemia 784
9 Avastin plus commonly used chemotherapies improves time without the disease getting worse 692
10 "Roche Continents" takes place for the third time 489
11 European Commission approves broader label for Avastin 613
12 MabThera receives positive opinion in Europe for treating patients whose chronic lymphocytic leukaemia returns 560
13 Xeloda in combination with oxaliplatin shown to be effective in early colon cancer 690
14 Roche announces new two-year data from the LITHE study 620
15 Roche provides additional donation of 5.65 million packs of Tamiflu to WHO 526
16 Roche rapidly responds to WHO request to deploy Rapid Response Stockpiles of Tamiflu 413
17 Roche strongly outperforms market in first quarter 464
18 Roche Diabetes Care supports "Changing Diabetes in Children" 725
19 Roche Annual General Meeting: dividend raised by 9 percent 729
20 Immune-boosting effect of Pegasys provides patients with the chance for a clinical cure 730
 
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